Dermal Research Compound | GHK-Cu 10mg + TB-500 10mg + BPC-157 5mg
Overview
Glow is a proprietary multi-peptide research blend designed for investigational dermatology and skin biology studies. It combines three well-studied peptides — GHK-Cu, TB-500, and BPC-157 — each with distinct but complementary mechanisms relevant to skin regeneration, matrix repair, and dermal health.
The rationale behind this blend is to simultaneously target multiple pathways involved in skin biology: extracellular matrix synthesis (GHK-Cu), cellular migration and anti-inflammation (TB-500), and tissue protection with angiogenesis (BPC-157).
Component Research
GHK-Cu (10mg)
- Stimulates collagen I, III, elastin, and proteoglycan synthesis in dermal fibroblasts (Siméon et al., 2000).
- Modulates 4,000+ genes including upregulation of TIMPs and suppression of MMPs for controlled remodeling (Pickart et al., 2012).
- SOD-mimic antioxidant activity protects against UV-induced oxidative stress.
- Outperformed vitamin C and retinol creams in collagen production studies (Finkley et al., 2005).
TB-500 (10mg)
- Active fragment of thymosin beta-4 — promotes keratinocyte and fibroblast migration to wound sites (Malinda et al., 1999).
- Anti-inflammatory: reduces TNF-α, IL-1β, and IL-6 in dermal tissue models.
- Anti-fibrotic properties: promotes organized collagen deposition over scar tissue formation.
- Promotes angiogenesis in ischemic tissue, improving nutrient delivery to skin (Goldstein et al., 2005).
BPC-157 (5mg)
- VEGF-mediated angiogenesis: promotes new microvasculature in healing tissue (Sikiric et al., 2018).
- Cytoprotective: protects fibroblasts and keratinocytes against oxidative damage.
- Accelerates epithelial cell migration and wound closure in skin models (Tkalcevic et al., 2007).
- Modulates NO system for improved tissue perfusion.
Research Areas
- Skin radiance: Melanocyte and keratinocyte modulation for complexion quality and evenness.
- Dermal matrix repair: Synergistic ECM protein synthesis — collagen, elastin, hyaluronic acid.
- Photoprotection: UV-induced damage mitigation in keratinocyte models. Reduced sunburn cell formation.
- Anti-aging: Cellular turnover, senescence marker modulation, and telomere-associated gene expression.
- Wound healing: Accelerated re-epithelialization and organized tissue remodeling.
Preliminary Findings
- Increased procollagen type I and III levels in fibroblast cultures vs. individual peptides alone.
- Reduced MMP-1 and MMP-9 activity in UV-stressed skin models by 40-60%.
- Improved skin hydration markers (hyaluronic acid synthase upregulation).
- Enhanced keratinocyte migration speed in scratch assay models.
- Reduced inflammatory cytokine expression in irritant-challenged skin explants.
Related product: Glow — Janoshik-tested, COA included, research use only.
Disclaimer: This information is compiled from published peer-reviewed research for educational purposes only. Grey Research compounds are intended for in vitro research and laboratory use only. Not for human consumption.
Certificate of Analysis
Independent third-party HPLC lab test by Janoshik Analytical. Every batch is tested before release.
Click to view full-size lab report.